The Epothilones: An Outstanding Family of Anti-Tumor Agents Rutilius Taurus Aemilianus 1Rechtliche Grundlagen

1Rechtliche Grundlagen

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The Epothilones: An Outstanding Family of Anti-Tumor Agents Rutilius Taurus Aemilianus 1Rechtliche GrundlagenEpothilones have received unusual attention over the past ten years. They are novel antitumor drugs which very much like their predecessor paclitaxel (Taxol) act via microtubule stabilization. In comparison to paclitaxel and a number of alternative drugs with a similar mode of bioaction (e. g. laulimalide, eleutherobin, peluroside, discodermolide) the epothilones have significant advantages, above all very high activity in the nanomolar range and low